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A polypeptide is a chain of 20-50 amino acids held together by a peptide bond. Amino acids are the building blocks of peptide bonds and are important components of protein structure.

The twenty-one amino acids used to create and maintain life contain an amino group, a carboxyl group, an alpha carbon atom, a singular hydrogen atom, and a side chain (R group). The R group is the only part of the amino acid structure that changes. When this changes, it determines the kind of amino acid that is formed and its structure in the body.

However, polypeptides are created when singular amino acids join together by a peptide bond.

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